Antibody-Binding Proteins and Conjugates
Biotium Testosterone(4E1G2), CF488A conjugate, 0.1mg/mL
This MAb is highly specific to testosterone. Its affinity constant for testosterone is ~1010 M-1. In competitive binding immunoassay, it reacts with testosterone 100%, 11-beta-hydroxy testosterone 3.3%, 17-alpha-methyl testosterone <0.1%, 5-alpha DHT 0.8%, estradiol <0.1% and progesterone <0.1%. Testosterone, a steroid hormone from the androgen group, is derived from cholesterol. Testosterone is primarily secreted in the testes, but the ovaries and adrenal glands also produce smaller amounts. It is the principal male sex hormone and is responsible for the maturation of sex organs and the development of male secondary sex characteristics. The hormone is also involved in the growth of muscle mass and increases bone density and maturation. It functions by activating the androgen receptor and converting to estradiol and activation of estrogen receptors. Testosterone has been employed therapeutically to treat many conditions including infertility, lack of libido, osteopor
Jackson Immuno Research Labs Brilliant Violet™ 421-ChromPure Donkey IgG whole molecule
Brilliant Violet™ 421-ChromPure Donkey IgG whole molecule
Abcam Gold Conjugation Kit (80nm, 20 OD), 1 x 5UG
80nm Gold conjugation / labeling in < 4 hrs with 30 secs hands-on time using Gold Conjugation Kit (80nm, 20 OD) ab154876. 100% antibody recovery.
The product is subject to the following: Abcam Restricted Use Statement
Jackson Immuno Research Labs Brilliant Violet™ 421-ChromPure Goat IgG whole molecule
Brilliant Violet™ 421-ChromPure Goat IgG whole molecule
Biotium CD282 / TLR2(TLR2/221), CF568 conjugate, 0.1mg/mL
This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
Cayman Chemical Cefalothin (sodium salt), Purity: ≥98%, CAS: 58-71-9, 500 mg
A β-lactam cephalosporin antibiotic; inhibits the growth of various Gram-positive and Gram-negative bacteria, including several strains of S. pyogenes, S. aureus, C. tetani, N. gonorrhoeae, Salmonella, and Shigella (MICs = 0.1-0.2, 0.312-0.625, 0.078, 1.25, 1.56-6.25, and 3.12-12.5 μg/ml, respectively); binds to E. coli PBPs (IC50s = S. pyogenes, D. pneumoniae, and S. aureus
Abcam mFluor™ Red 700 Conjugation Kit, 100UG
mFluor™ Red 700 conjugation / labeling in < 4 hrs with 30 secs hands-on time using mFluor™ Red 700 Conjugation Kit ab312807. 100% antibody recovery.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Bialaphos (sodium salt), Purity: ≥95%, CAS: 71048-99-2, 50 mg
A natural non-selective phytotoxin that is converted in vivo to the active agent phosphinothricin, which inhibits glutamine synthetase (Ki = 6.1 µM); used in the selection of transgenic plants that express the bar gene, usually under the control of a constitutively active viral promoter
Jackson Immuno Research Labs Rhodamine (TRITC)-IgG Fraction Monoclonal Mouse Anti-Fluorescein (FITC)
Rhodamine (TRITC)-IgG Fraction Monoclonal Mouse Anti-Fluorescein (FITC)
Jackson Immuno Research Labs Peroxidase-ChromPure Chicken IgY (IgG) whole molecule
Peroxidase-ChromPure Chicken IgY (IgG) whole molecule
Cayman Chemical GC376 (sodium salt), Purity: ≥90%, CAS: 1416992-39-6, 50 mg
An inhibitor of 3C- and 3C-like proteases; inhibits recombinant poliovirus, FMDV, and HRV 3C proteases (IC50s = 1.77, 1.16, and 0.2 µM, respectively); inhibits recombinant Norwalk virus, MD145 virus, TGEV, and SARS-CoV 3C-like proteases (IC50s = 0.49, 0.96, 0.82 and 4.35 µM, respectively); inhibits the cytopathic effect of SARS-CoV-2 in infected Vero E6 cells (EC50 = 3.37 µM); reduces liver viral titers by 9.86- and 21.99-fold in a model of MHV A59 infection at doses of 50 and 100 mg/kg per day, respectively
Biotium CD56 / NCAM(123C3.D5), CF647 conjugate, 0.1mg/mL
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are
Jackson Immuno Research Labs Peroxidase-ChromPure Rabbit IgG whole molecule
Peroxidase-ChromPure Rabbit IgG whole molecule
Biotium Myogenin(MGN185), CF488A conjugate, 0.1mg/mL
Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms tumor.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes